Novel Role for SGK3 in Glucose Homeostasis Revealed in SGK3/Akt2 Double-Null Mice

The phosphatidylinositol-3-kinase-dependent kinase, Akt2, plays a central role in mediating insulin effects in glucose-metabolizing tissues. Akt2 knockout mice display insulin resistance with a reactive increase in pancreatic islet mass and hyperinsulinemia. The related phosphatidylinositol-3-kinase...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yao, Li-Jun, McCormick, James A., Wang, Jian, Yang, Katherine Y., Kidwai, Atif, Colussi, Gian Luca, Boini, Krishna M., Birnbaum, Morris J., Lang, Florian, German, Michael S., Pearce, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2011
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231839/
https://ncbi.nlm.nih.gov/pubmed/21980074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0329
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