A chimeric plasmid from cDNA clones of poliovirus and coxsackievirus produces a recombinant virus that is temperature-sensitive.

We have inserted a 405-nucleotide fragment from the 5' noncoding region of the coxsackievirus B3 genome into an infectious cDNA copy of the poliovirus RNA genome. Transfection of plasmid DNA containing this hybrid genome construct into cultured monkey cells produced infectious virus. Recombinant vir...

Descrición completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Semler, B L, Johnson, V H, Tracy, S
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1986
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323167/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3006071/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.6.1777
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!