Protein kinase C phosphorylates topoisomerase II: topoisomerase activation and its possible role in phorbol ester-induced differentiation of HL-60 cells.

DNA topoisomerase II from Drosophila was phosphorylated effectively by protein kinase C. With a Km of about 100 nM, the reaction was rapid, occurring at 4 degrees C as well as at 30 degrees C and requiring as little as 0.6 ng of the protein kinase per 170 ng of topoisomerase. About 0.85 mol of phosp...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sahyoun, N, Wolf, M, Besterman, J, Hsieh, T, Sander, M, LeVine, H, Chang, K J, Cuatrecasas, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323131/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3006058/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.6.1603
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!