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Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain.

The neutral endopeptidase EC 3.4.24.11, also designated enkephalinase, has been visualized by in vitro autoradiography using the tritiated inhibitor [3H]-N-[(2RS)-3-hydroxyaminocarbonyl-2-benzyl-1-oxopropyl] glycine, ([3H]HACBO-Gly). Specific binding of [3H]HACBO-Gly (Kd = 0.4 +/- 0.05 nM) correspon...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Waksman, G, Hamel, E, Fournié-Zaluski, M C, Roques, B P
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323109/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3006054/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.5.1523
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