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Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain.

The neutral endopeptidase EC 3.4.24.11, also designated enkephalinase, has been visualized by in vitro autoradiography using the tritiated inhibitor [3H]-N-[(2RS)-3-hydroxyaminocarbonyl-2-benzyl-1-oxopropyl] glycine, ([3H]HACBO-Gly). Specific binding of [3H]HACBO-Gly (Kd = 0.4 +/- 0.05 nM) correspon...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Waksman, G, Hamel, E, Fournié-Zaluski, M C, Roques, B P
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323109/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3006054/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.5.1523
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