Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa.

Congenital absence of platelet glycoproteins IIb and IIIa (GPIIb and GPIIIa) results in a severe bleeding disorder characterized by defective platelet aggregation and failure of fibrinogen to bind to platelets. GPIIb is a two-chain protein containing disulfide-linked alpha and beta subunits. GPIIb a...

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Detaylı Bibliyografya
Asıl Yazarlar: Bray, P F, Rosa, J P, Lingappa, V R, Kan, Y W, McEver, R P, Shuman, M A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1986
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC323100/
https://ncbi.nlm.nih.gov/pubmed/3006053
Etiketler: Etiketle
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