Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa.

Congenital absence of platelet glycoproteins IIb and IIIa (GPIIb and GPIIIa) results in a severe bleeding disorder characterized by defective platelet aggregation and failure of fibrinogen to bind to platelets. GPIIb is a two-chain protein containing disulfide-linked alpha and beta subunits. GPIIb a...

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Bibliografische gegevens
Hoofdauteurs: Bray, P F, Rosa, J P, Lingappa, V R, Kan, Y W, McEver, R P, Shuman, M A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1986
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC323100/
https://ncbi.nlm.nih.gov/pubmed/3006053
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