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Statistical considerations for linkage analysis using recombinant inbred strains and backcrosses.
Recombinant inbred (RI) mouse strains are extremely useful for gene mapping, especially for establishing preliminary map positions for new loci. However, the usual statistical analysis applied to such experiments may lead to erroneous conclusions about linkage unless unusually stringent criteria are...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1986
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC323088/ https://ncbi.nlm.nih.gov/pubmed/3456595 |
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