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Two- and Three-Locus Tests for Linkage Analysis Using Recombinant Inbred Lines

We consider fixed recombinant inbred lines (RILs) derived either by selfing or by full-sib mating; when applicable, we also consider intermated recombinant inbreds (IRIs). First, we show that the usual estimate of recombination fraction based on RIL data is biased, and we provide an estimate where t...

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Detalhes bibliográficos
Main Authors: Martin, Olivier C., Hospital, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2006 by the Genetics Society of America 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461428/
https://ncbi.nlm.nih.gov/pubmed/16489236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.047175
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