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The flavonoid scaffold as a template for the design of modulators of the vascular Ca(v)1.2 channels

BACKGROUND AND PURPOSE: Previous studies have pointed to the plant flavonoids myricetin and quercetin as two structurally related stimulators of vascular Ca(v)1.2 channel current (I(Ca1.2)). Here we have tested the proposition that the flavonoid structure confers the ability to modulate Ca(v)1.2 cha...

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Autors principals: Saponara, S, Carosati, E, Mugnai, P, Sgaragli, G, Fusi, F
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230815/
https://ncbi.nlm.nih.gov/pubmed/21557738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01476.x
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