The flavonoid scaffold as a template for the design of modulators of the vascular Ca(v)1.2 channels

BACKGROUND AND PURPOSE: Previous studies have pointed to the plant flavonoids myricetin and quercetin as two structurally related stimulators of vascular Ca(v)1.2 channel current (I(Ca1.2)). Here we have tested the proposition that the flavonoid structure confers the ability to modulate Ca(v)1.2 cha...

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Bibliografiske detaljer
Main Authors: Saponara, S, Carosati, E, Mugnai, P, Sgaragli, G, Fusi, F
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2011
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230815/
https://ncbi.nlm.nih.gov/pubmed/21557738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01476.x
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