The protective effect of tianeptine on Gp120-induced apoptosis in astroglial cells: role of GS and NOS, and NF-κB suppression

BACKGROUND AND PURPOSE: Tianeptine is an antidepressant affecting the glutamatergic system. In spite of its proven clinical efficacy, molecular effects of tianeptine are not entirely clear. Tianeptine modulates cytokine expression in the CNS and protects the hippocampus from chronic stress effects....

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Detalhes bibliográficos
Main Authors: Janda, Elzbieta, Visalli, Valeria, Colica, Carmela, Aprigliano, Serafina, Musolino, Vincenzo, Vadalà, Nuria, Muscoli, Carolina, Sacco, Iolanda, Iannone, Michelangelo, Rotiroti, Domenicantonio, Spedding, Michael, Mollace, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230807/
https://ncbi.nlm.nih.gov/pubmed/21175585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01172.x
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