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Design and Synthesis of Biologically Active Peptides: A ‘Tail’ of Amino Acids can Modulate Activity of Synthetic Cyclic Peptides
In earlier work, we synthesized a cyclic 9-amino acid peptide (AFPep, cyclo[EKTOVNOGN]) and showed it to be useful for prevention and therapy of breast cancer. In an effort to explore the structure-function relationships of AFPep, we have designed analogs that bear a short ‘tail’ (one or two amino a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230782/ https://ncbi.nlm.nih.gov/pubmed/22015269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2011.10.007 |
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