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Extra-thymically induced regulatory T cells: do they have potential in disease prevention?

Fopx3(+) Treg safeguard against autoimmune diseases and immune pathology. The extrathymic conversion of naïve T cells into Foxp3(+) regulatory T cells can be achieved in vivo by the delivery of strong-agonist ligands under subimmunogenic conditions. Tolerogenic vaccination with strong-agonist mimeto...

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Detalhes bibliográficos
Main Authors: Daniel, Carolin, von Boehmer, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230715/
https://ncbi.nlm.nih.gov/pubmed/21724411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2011.06.004
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