Cargando...

Disparate degrees of hypervariable loop flexibility control T cell receptor cross-reactivity, specificity, and binding mechanism

αβ T cell receptors recognize multiple antigenic peptides bound and presented by major histocompatibility complex molecules. TCR cross-reactivity has been attributed in part to flexibility of the complementarity-determining region loops, yet there have been limited direct studies of loop dynamics to...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Scott, Daniel R., Borbulevych, Oleg. Y, Piepenbrink, Kurt H., Corcelli, Steven A., Baker, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230710/
https://ncbi.nlm.nih.gov/pubmed/22019736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.10.006
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!