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The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis
Telomerase is a ribonucleoprotein (RNP) enzyme that maintains the ends of linear eukaryotic chromosomes and whose activation is a hallmark of 90% of all cancers. This RNP minimally contains a reverse transcriptase protein subunit (TERT) that catalyzes telomeric DNA synthesis and an RNA subunit (TER)...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230705/ https://ncbi.nlm.nih.gov/pubmed/22101935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2174 |
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