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The Crystal Structure Analysis of Group B Streptococcus Sortase C1: A Model for the ‘lid’ Movement upon Substrate Binding
A unique feature of the class-C-type sortases, enzymes essential for Gram-positive pilus biogenesis, is the presence of a flexible ‘lid’ anchored in the active site. However, the mechanistic details of the ‘lid’ displacement, suggested to be a critical prelude for enzyme catalysis, are not yet known...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230703/ https://ncbi.nlm.nih.gov/pubmed/22033482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.10.017 |
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