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High Dimensional Endophenotype Ranking in the Search for Major Depression Risk Genes

BACKGROUND: Despite overwhelming evidence that major depression is highly heritable, recent studies have localized only a single depression-related locus reaching genome-wide significance and have yet to identify a causal gene. Focusing on family-based studies of quantitative intermediate phenotypes...

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Hlavní autoři: Glahn, David C, Curran, Joanne E, Winkler, Anderson M, Carless, Melanie A, Kent, Jack W, Charlesworth, Jac C, Johnson, Matthew P, Göring, Harald HH, Cole, Shelley A, Dyer, Thomas D, Moses, Eric K, Olvera, Rene L, Kochunov, Peter, Duggirala, Ravi, Fox, Peter T, Almasy, Laura, Blangero, John
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230692/
https://ncbi.nlm.nih.gov/pubmed/21982424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.08.022
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