High Dimensional Endophenotype Ranking in the Search for Major Depression Risk Genes

BACKGROUND: Despite overwhelming evidence that major depression is highly heritable, recent studies have localized only a single depression-related locus reaching genome-wide significance and have yet to identify a causal gene. Focusing on family-based studies of quantitative intermediate phenotypes...

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Detalhes bibliográficos
Main Authors: Glahn, David C, Curran, Joanne E, Winkler, Anderson M, Carless, Melanie A, Kent, Jack W, Charlesworth, Jac C, Johnson, Matthew P, Göring, Harald HH, Cole, Shelley A, Dyer, Thomas D, Moses, Eric K, Olvera, Rene L, Kochunov, Peter, Duggirala, Ravi, Fox, Peter T, Almasy, Laura, Blangero, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230692/
https://ncbi.nlm.nih.gov/pubmed/21982424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.08.022
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