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RNA targets of wild-type and mutant FET family proteins

FUS, EWSR1 and TAF15, constituting the FET protein family, are abundant, highly conserved RNA-binding proteins with important roles in oncogenesis and neuronal disease, yet their RNA targets and recognition element are unknown. Using PAR-CLIP, we defined global RNA targets of all human FET proteins...

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Detalhes bibliográficos
Main Authors: Hoell, Jessica I., Larsson, Erik, Runge, Simon, Nusbaum, Jeffrey D., Duggimpudi, Sujitha, Farazi, Thalia A., Hafner, Markus, Borkhardt, Arndt, Sander, Chris, Tuschl, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230689/
https://ncbi.nlm.nih.gov/pubmed/22081015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2163
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