Antiviral Activity of Bay 41-4109 on Hepatitis B Virus in Humanized Alb-uPA/SCID Mice

Current treatments for HBV chronic carriers using interferon alpha or nucleoside analogues are not effective in all patients and may induce the emergence of HBV resistant strains. Bay 41-4109, a member of the heteroaryldihydropyrimidine family, inhibits HBV replication by destabilizing capsid assemb...

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Autores principales: Brezillon, Nicolas, Brunelle, Marie-Noëlle, Massinet, Hélène, Giang, Eric, Lamant, Céline, DaSilva, Lucie, Berissi, Sophie, Belghiti, Jacques, Hannoun, Laurent, Puerstinger, Gherard, Wimmer, Eva, Neyts, Johan, Hantz, Olivier, Soussan, Patrick, Morosan, Serban, Kremsdorf, Dina
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230577/
https://ncbi.nlm.nih.gov/pubmed/22162746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025096
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