HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA Mice

Hepatitis C virus (HCV) is a blood-borne pathogen and a major cause of liver disease worldwide. Gene expression profiling was used to characterize the transcriptional response to HCV H77c infection. Evidence is presented for activation of innate antiviral signaling pathways as well as induction of l...

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Detalhes bibliográficos
Main Authors: Joyce, Michael A., Walters, Kathie-Anne, Lamb, Sue-Ellen, Yeh, Mathew M., Zhu, Lin-Fu, Kneteman, Norman, Doyle, Jason S., Katze, Michael G., Tyrrell, D. Lorne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647842/
https://ncbi.nlm.nih.gov/pubmed/19242562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000291
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