HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA Mice

Hepatitis C virus (HCV) is a blood-borne pathogen and a major cause of liver disease worldwide. Gene expression profiling was used to characterize the transcriptional response to HCV H77c infection. Evidence is presented for activation of innate antiviral signaling pathways as well as induction of l...

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Main Authors: Joyce, Michael A., Walters, Kathie-Anne, Lamb, Sue-Ellen, Yeh, Mathew M., Zhu, Lin-Fu, Kneteman, Norman, Doyle, Jason S., Katze, Michael G., Tyrrell, D. Lorne
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647842/
https://ncbi.nlm.nih.gov/pubmed/19242562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000291
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