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Histone H2B ubiquitination and beyond: Regulation of nucleosome stability, chromatin dynamics and the trans-histone H3 methylation

Regulation of Set1-COMPASS-mediated H3K4 methylation and Dot1-mediated H3K79 methylation by H2BK123 ubiquitination (H2Bub1) is an evolutionarily conserved trans-histone crosstalk mechanism. How H2Bub1 impacts chromatin structure and affects Set1-COMPASS/Dot1 functions has not been fully defined. Ubi...

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Detalhes bibliográficos
Main Authors: Chandrasekharan, Mahesh B, Huang, Fu, Sun, Zu-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230548/
https://ncbi.nlm.nih.gov/pubmed/20523115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.5.6.12314
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