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Ubiquitination of histone H2B regulates chromatin dynamics by enhancing nucleosome stability
The mechanism by which ubiquitination of histone H2B (H2Bub1) regulates H3-K4 and -K79 methylation and the histone H2A-H2B chaperone Spt16-mediated nucleosome dynamics during transcription is not fully understood. Upon investigating the effect of H2Bub1 on chromatin structure, we find that contrary...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757834/ https://ncbi.nlm.nih.gov/pubmed/19805358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907862106 |
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