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Ubiquitination of histone H2B regulates chromatin dynamics by enhancing nucleosome stability

The mechanism by which ubiquitination of histone H2B (H2Bub1) regulates H3-K4 and -K79 methylation and the histone H2A-H2B chaperone Spt16-mediated nucleosome dynamics during transcription is not fully understood. Upon investigating the effect of H2Bub1 on chromatin structure, we find that contrary...

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Detalhes bibliográficos
Main Authors: Chandrasekharan, Mahesh B., Huang, Fu, Sun, Zu-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757834/
https://ncbi.nlm.nih.gov/pubmed/19805358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907862106
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