Mutations activating human c-Ha-ras1 protooncogene (HRAS1) induced by chemical carcinogens and depurination.

In vitro modification of plasmids containing the human c-Ha-ras1 protooncogene (HRAS1) with the ultimate carcinogens N-acetoxy-2-acetylaminofluorene and r-7, t-8-dihydroxy-t-9, 10-epoxy-7,8,9,10-tetrahydrobenzo[alpha]pyrene (anti-BPDE) generated a transforming oncogene when the modified DNA was tran...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Vousden, K H, Bos, J L, Marshall, C J, Phillips, D H
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1986
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323047/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3513171/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.5.1222
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