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Additivity of Pyrethroid Actions on Sodium Influx in Cerebrocortical Neurons in Primary Culture

Background: Pyrethroid insecticides bind to voltage-gated sodium channels and modify their gating kinetics, thereby disrupting neuronal function. Although previous work has tested the additivity of pyrethroids in vivo, this has not been assessed directly at the primary molecular target using a funct...

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Autors principals: Cao, Zhengyu, Shafer, Timothy J., Crofton, Kevin M., Gennings, Chris, Murray, Thomas F.
Format: Artigo
Idioma:Inglês
Publicat: National Institute of Environmental Health Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230403/
https://ncbi.nlm.nih.gov/pubmed/21665567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1003394
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