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Initial interrogation, confirmation and fine mapping of modifying genes: STAT3, IL1B and IFNGR1 determine cystic fibrosis disease manifestation

We have used a stepwise approach consisting of initial interrogation, confirmation and fine mapping to analyze STAT3, IL1B and IFNGR1 as modifiers of cystic fibrosis disease building upon the data and sample collection of the European Cystic Fibrosis Twin and Sibling Study. We have observed direct c...

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Detalhes bibliográficos
Main Authors: Labenski, Heike, Hedtfeld, Silke, Becker, Tim, Tümmler, Burkhard, Stanke, Frauke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230365/
https://ncbi.nlm.nih.gov/pubmed/21731057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.129
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