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Small molecule inhibitors reveal Niemann-Pick C1 is essential for ebolavirus infection
Ebolavirus (EboV) is a highly pathogenic enveloped virus that causes outbreaks of zoonotic infection in Africa. The clinical symptoms are manifestations of the massive production of pro-inflammatory cytokines in response to infection(1) and in many outbreaks, mortality exceeds 75%. The unpredictable...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230319/ https://ncbi.nlm.nih.gov/pubmed/21866101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10380 |
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