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Gli3 mediates cell survival and sensitivity to cyclopamine in pancreatic cancer
Activation of the hedgehog (HH) pathway plays a critical role in the development and continued growth of pancreatic adenocarcinoma (PA C). Cyclopamine, a HH pathway inhibitor, has been shown to suppress PA C cell proliferation in vitro and in vivo. However, the molecular basis of response to cyclopa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230294/ https://ncbi.nlm.nih.gov/pubmed/20814245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.9.13252 |
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