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An IV for the RCT: using instrumental variables to adjust for treatment contamination in randomised controlled trials

Although the randomised controlled trial is the “gold standard” for studying the efficacy and safety of medical treatments, it is not necessarily free from bias. When patients do not follow the protocol for their assigned treatment, the resultant “treatment contamination” can produce misleading find...

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Detalhes bibliográficos
Main Authors: Sussman, Jeremy B, Hayward, Rodney A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group Ltd. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230230/
https://ncbi.nlm.nih.gov/pubmed/20442226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmj.c2073
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