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Cloning and expression of a cDNA coding for the anticoagulant hirudin from the bloodsucking leech, Hirudo medicinalis.

Cloned cDNAs have been isolated that encode a variant of hirudin, a potent thrombin inhibitor that is secreted by the salivary glands of the medicinal leech, Hirudo medicinalis. This variant probably corresponds to a form that has been purified from leech heads but differs in amino acid sequence fro...

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Autors principals: Harvey, R P, Degryse, E, Stefani, L, Schamber, F, Cazenave, J P, Courtney, M, Tolstoshev, P, Lecocq, J P
Format: Artigo
Idioma:Inglês
Publicat: 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC323015/
https://ncbi.nlm.nih.gov/pubmed/3513162
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