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Cell-free synthesis of the hirudin variant 1 of the blood-sucking leech Hirudo medicinalis
Synthesis and purification of peptide drugs for medical applications is a challenging task. The leech-derived factor hirudin is in clinical use as an alternative to heparin in anticoagulatory therapies. So far, recombinant hirudin is mainly produced in bacterial or yeast expression systems. We descr...
Tallennettuna:
| Julkaisussa: | Sci Rep |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7666225/ https://ncbi.nlm.nih.gov/pubmed/33188246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76715-w |
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