Role of Substance P in the Regulation of Glucose Metabolism via Insulin Signaling-Associated Pathways

Substance P (SP), encoded by the tachykinin 1 (Tac1) gene, is the most potent tachykinin ligand for the high-affinity neurokinin-1 receptor (NK-1R). We previously reported that NK-1R-deficient mice show less weight gain and reduced circulating levels of leptin and insulin in response to a high-fat d...

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Detalhes bibliográficos
Main Authors: Karagiannides, Iordanes, Bakirtzi, Kyriaki, Kokkotou, Efi, Stavrakis, Dimitris, Margolis, Kara Gross, Thomou, Thomas, Giorgadze, Nino, Kirkland, James L., Pothoulakis, Charalabos
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Diabetes-Insulin-Glucagon-Gastrointestinal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230056/
https://ncbi.nlm.nih.gov/pubmed/22009727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1170
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