Noninvasive Analytical Estimation of Endogenous GnRH Drive: Analysis Using Graded Competitive GnRH-Receptor Antagonism and a Calibrating Pulse of Exogenous GnRH

Homeostatic control of endocrine systems proceeds via feedforward (agonistic, stimulatory) and feedback (antagonistic, inhibitory) interactions mediated via implicit dose-response functions. However, neither the feedback/feedforward pathways nor the dose-response interfaces are directly observed in...

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Autors principals: Keenan, Daniel M., Clarke, Iain J., Veldhuis, Johannes D.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2011
Matèries:
Neuroendocrinology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230048/
https://ncbi.nlm.nih.gov/pubmed/22028450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1461
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