XRCC1 Coordinates Disparate Responses and Multiprotein Repair Complexes Depending on the Nature and Context of the DNA Damage

XRCC1 is a scaffold protein capable of interacting with several DNA repair proteins. Here we provide evidence for the presence of XRCC1 in different complexes of sizes from 200 to 1500 kDa, and we show that immunoprecipitates using XRCC1 as bait are capable of complete repair of AP sites via both sh...

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Detalhes bibliográficos
Main Authors: Hanssen-Bauer, Audun, Solvang-Garten, Karin, Sundheim, Ottar, Peña-Diaz, Javier, Andersen, Sonja, Slupphaug, Geir, Krokan, Hans E, Wilson, David M, Akbari, Mansour, Otterlei, Marit
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229989/
https://ncbi.nlm.nih.gov/pubmed/21786338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20663
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