Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes

Uracil-DNA glycosylase, UNG2, interacts with PCNA and initiates post-replicative base excision repair (BER) of uracil in DNA. The DNA repair protein XRCC1 also co-localizes and physically interacts with PCNA. However, little is known about whether UNG2 and XRCC1 directly interact and participate in...

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Huvudupphovsmän: Akbari, Mansour, Solvang-Garten, Karin, Hanssen-Bauer, Audun, Lieske, Nora Valeska, Pettersen, Henrik Sahlin, Pettersen, Grete Klippenvåg, Wilson, David M., Krokan, Hans E., Otterlei, Marit
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901844/
https://ncbi.nlm.nih.gov/pubmed/20466601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.04.002
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