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Nuclear protein accumulation in cellular senescence and organismal aging revealed with a novel single-cell resolution fluorescence microscopy assay

Replicative cellular senescence was discovered some 50 years ago. The phenotypes of senescent cells have been investigated extensively in cell culture, and found to affect essentially all aspects of cellular physiology. The relevance of cellular senescence in the context of age-associated pathologie...

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書誌詳細
主要な著者: De Cecco, Marco, Jeyapalan, Jessie, Zhao, Xiaoai, Tamamori-Adachi, Mimi, Sedivy, John M.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2011
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229972/
https://ncbi.nlm.nih.gov/pubmed/22006542
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