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Inhibition of tumor-cell-mediated extracellular matrix destruction by a fibroblast proteinase inhibitor, protease nexin I.

Human fibrosarcoma (HT-1080) cells, in contrast to normal fibroblasts, rapidly hydrolyze the glycoprotein, collagen, and elastin extracellular matrix (ECM) synthesized by cultured rat aortic smooth muscle cells. This degradation occurs at a rapid rate in the presence of serum, indicating that the ce...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Bergman, B L, Scott, R W, Bajpai, A, Watts, S, Baker, J B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1986
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322997/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3513169/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.4.996
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