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Fibroblast Growth Factor (FGF) regulates human neuroectoderm specification through ERK1/2-PARP-1 pathway
FGF signaling and PAX6 transcription are required for neuroectoderm specification of human embryonic stem cells (hESCs). In this study we asked how FGF signaling leads to PAX6 transcription and neuroectoderm specification from hESCs. Under a chemically defined medium, FGF inhibition blocked phosphor...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3229919/ https://ncbi.nlm.nih.gov/pubmed/21997878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.758 |
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