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Pax6 is a human neuroectoderm cell fate determinant

The transcriptional regulation of neuroectoderm (NE) specification is unknown. Here we show that Pax6 is uniformly expressed in early NE cells of human fetuses and those differentiated from human embryonic stem cells (hESCs). This contrasts the later expression of Pax6 in restricted mouse brain regi...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaoqing, Huang, Cindy T., Chen, Jing, Pankratz, Matthew T., Xi, Jiajie, Li, Jin, Yang, Ying, LaVaute, Timothy M., Li, Xue-Jun, Ayala, Melvin, Bondarenko, Gennadiy I., Du, Zhong-Wei, Jin, Ying, Golos, Thaddeus G., Zhang, Su-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904346/
https://ncbi.nlm.nih.gov/pubmed/20621053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.04.017
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