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Inhibition of splicing but not cleavage at the 5' splice site by truncating human beta-globin pre-mRNA.

Human beta-globin mRNAs truncated in the second exon or in the first intron have been processed in vitro in a HeLa cell nuclear extract. Transcripts containing a fragment of the second exon as short as 53 nucleotides are efficiently spliced, whereas transcripts truncated 24 or 14 nucleotides downstr...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Furdon, P J, Kole, R
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1986
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322983/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2937057/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.4.927
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