Inhibition of splicing but not cleavage at the 5' splice site by truncating human beta-globin pre-mRNA.
Human beta-globin mRNAs truncated in the second exon or in the first intron have been processed in vitro in a HeLa cell nuclear extract. Transcripts containing a fragment of the second exon as short as 53 nucleotides are efficiently spliced, whereas transcripts truncated 24 or 14 nucleotides downstr...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1986
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322983/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2937057/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.4.927 |
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