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Bacteriophage T4 DNA topoisomerase mediates illegitimate recombination in vitro.

We have found that purified T4 DNA topoisomerase promotes recombination between two phage lambda DNA molecules in an in vitro system. In this cross, T4 DNA topoisomerase alone is able to catalyze the recombination and produce a linear monomer recombinant DNA that can be packaged in vitro. ATP is not...

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Bibliografiske detaljer
Hovedforfatter: Ikeda, H
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC322982/
https://ncbi.nlm.nih.gov/pubmed/3006033
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