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Role of proline peptide bond isomerization in unfolding and refolding of ribonuclease.

The isomerization of the proline peptide bond between tyrosine-92 and proline-93 in bovine pancreatic ribonuclease A has been investigated in the unfolded protein as well as during the slow refolding process. This bond is in the cis state in the native protein. By comparison of various homologous ri...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Schmid, F X, Grafl, R, Wrba, A, Beintema, J J
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1986
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322972/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3456571/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.4.872
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