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Role of proline peptide bond isomerization in unfolding and refolding of ribonuclease.

The isomerization of the proline peptide bond between tyrosine-92 and proline-93 in bovine pancreatic ribonuclease A has been investigated in the unfolded protein as well as during the slow refolding process. This bond is in the cis state in the native protein. By comparison of various homologous ri...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Schmid, F X, Grafl, R, Wrba, A, Beintema, J J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1986
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322972/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3456571/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.4.872
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