Altered microRNA expression in frontotemporal lobar degeneration with TDP-43 pathology caused by progranulin mutations

BACKGROUND: Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disorder that can be triggered through genetic or sporadic mechanisms. MicroRNAs (miRNAs) have become a major therapeutic focus as their pervasive expression and powerful regulatory roles in disease pathogenesis...

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Main Authors: Kocerha, Jannet, Kouri, Naomi, Baker, Matt, Finch, NiCole, DeJesus-Hernandez, Mariely, Gonzalez, John, Chidamparam, Kumaravel, Josephs, Keith A, Boeve, Bradley F, Graff-Radford, Neill R, Crook, Julia, Dickson, Dennis W, Rademakers, Rosa
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229715/
https://ncbi.nlm.nih.gov/pubmed/22032330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-527
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