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Effect of Cryogrinding on Chemical Stability of the Sparingly Water-Soluble Drug Furosemide
PURPOSE: To investigate the effect of cryogrinding on chemical stability of the diuretic agent furosemide and its mixtures with selected excipients. METHODS: Furosemide was ground at liquid nitrogen temperature for 30, 60, 120 and 180 min. Mixtures of furosemide-PVP and furosemide-inulin (1:1) were...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3229691/ https://ncbi.nlm.nih.gov/pubmed/21706267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0496-4 |
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