Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities.
The activity of leukotriene A4 (LTA4) synthase in crude human leukocyte homogenates was found to have a similar requirement for Ca2+ and ATP as had been noted previously for 5-lipoxygenase activity. Purification of the 5-lipoxygenase using ammonium sulfate fractionation, AcA 44 gel-filtration chroma...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322969/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3006030/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.4.857 |
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