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Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities.

The activity of leukotriene A4 (LTA4) synthase in crude human leukocyte homogenates was found to have a similar requirement for Ca2+ and ATP as had been noted previously for 5-lipoxygenase activity. Purification of the 5-lipoxygenase using ammonium sulfate fractionation, AcA 44 gel-filtration chroma...

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Bibliografski detalji
Glavni autori: Rouzer, C A, Matsumoto, T, Samuelsson, B
Format: Artigo
Jezik:Inglês
Izdano: 1986
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC322969/
https://ncbi.nlm.nih.gov/pubmed/3006030
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