Image-Based Genome-Wide siRNA Screen Identifies Selective Autophagy Factors

Selective autophagy involves the recognition and targeting of specific cargo, such as damaged organelles, misfolded proteins, or invading pathogens for lysosomal destruction(1–4). Yeast genetic screens have identified proteins required for different forms of selective autophagy, including cytoplasm-...

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Hlavní autoři: Orvedahl, Anthony, Sumpter, Rhea, Xiao, Guanghua, Ng, Aylwin, Zou, Zhongju, Tang, Yi, Narimatsu, Masahiro, Gilpin, Christopher, Sun, Qihua, Roth, Michael, Forst, Christian V., Wrana, Jeffrey L., Zhang, Ying E., Luby-Phelps, Katherine, Xavier, Ramnik, Xie, Yang, Levine, Beth
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229641/
https://ncbi.nlm.nih.gov/pubmed/22020285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10546
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